Senior Principal Scientist, Lab Head Medicinal Chemistry

Role Summary

Senior Principal Scientist, Lab Head Medicinal Chemistry based in Cambridge, MA. You will lead medicinal chemistry efforts within multidisciplinary drug discovery, applying deep scientific expertise to initiate, design, and direct medicinal chemistry programs in support of research goals. The role requires effective communication of scientific content to teams and stakeholders, mentorship of other medicinal chemists, and contribution to external scientific communities.

• The successful candidate is a proven, experienced team leader with a track record of success in medicinal chemistry and multidisciplinary drug discovery.
• A Senior Principal Scientist is responsible for applying deep scientific expertise and judgment to initiate, design, and direct medicinal chemistry in support of research goals.
• Is an expert in analyzing, interpreting and communicating scientific content to teams and stakeholders.
• Demonstrates continuous growth in depth and breadth of scientific knowledge and understanding of strategic goals of group, team and company.
• Successfully works as an impactful contributor, and as a leader of project teams and transverse initiatives; is an experienced and supportive manager and mentor of other medicinal chemists.
• Has an established and growing reputation in the external scientific community through high impact publications, productive scientific collaborations and active participation in conferences.

• PhD in Organic/Medicinal Chemistry with 7+ years of experience in a pharmaceutical/biopharmaceutical environment.
• Or Master’s degree in Organic Chemistry with 9+ years of experience in a pharmaceutical/biopharmaceutical environment.
• Or Bachelor’s degree with 12+ years of experience in a pharmaceutical/biopharmaceutical environment.
• Exceptional technical skills and demonstrated ability to work and thrive in a collaborative cross-functional team setting; proven ability to analyze complex data sets, draw conclusions, and design follow-on experiments.
• Experience in all phases of the small molecule discovery process from hit  candidate nomination.
• Demonstrated track record of intellectual contributions in drug discovery as evidenced by impactful peer-reviewed publications, presentations, patents, and project achievements.
• Demonstrated success leading multidisciplinary drug discovery projects from conception through key milestones.
• Proven track record mentoring and developing junior scientists with measurable impact on team performance and individual career growth.
• Experience working with CROs and external collaborators.
• Comfortable and efficient in fast moving complex global environment.

• PhD in Organic/Medicinal Chemistry, 7+ years of relevant industry experience; or
• Master’s degree in Organic Chemistry, 9+ years of relevant industry experience; or
• Bachelor’s degree, 12+ years of relevant industry experience.

• Analytical thinking and data-driven decision making
• Cross-functional collaboration and communication
• Project leadership and mentorship
• Experience with external collaborations and CROs