Sr Manager, Clinical Data Platform Engineer

Role Summary

Locations include Cambridge, US;
Gaithersburg, US;
London, United Kingdom;
Mainz, Germany. This full-time role maintains and enhances BioNTech’s GxP-aligned clinical data platform built on Databricks and AWS, implemented with Terraform-based Infrastructure-as-Code (IaC). The role ensures the platform's reliability, compliance, scalability, and security while supporting high-quality clinical data workflows. Collaborating closely with multidisciplinary teams, you will contribute to advancing BioNTech’s mission of revolutionizing medicine and improving global health.

• Partner with Solutions Architects to design and execute platform integrations and roadmaps
• Collaborate with Data Engineers to ensure reliable pipeline operations and scalable platform patterns
• Work alongside Clinical Data Managers to enable compliant access and workflow readiness
• Engage with Cloud, Security, and QA teams to ensure aligned operations within a validated environment
• Manage user provisioning and enforce validated configuration baselines for auditability controls
• Operate Databricks work spaces across environments while managing supporting AWS components

• Bachelor’s degree or equivalent experience in computer science, engineering, or related fields with 5–8+ years of experience in cloud-based data platforms (AWS), and 2–4+ years in Databricks administration, workspace configuration, and large-scale data ecosystems
• Experience in GxP/GCP environments, auditability, data integrity requirements, and regulated data systems
• Familiarity with clinical data ecosystems (CDR/ODR, CRO data ingestion, study onboarding processes)
• Strong understanding of the Product Life Cycle of software products
• Expertise in Databricks Delta Sharing, service principal management, and multi-workspace architectures
• Advanced troubleshooting skills across Databricks compute/runtime environments, AWS infrastructure components, and Terraform state management
• Proficiency in AWS IAM policies, KMS encryption services, Secrets Manager functionality, and S3 cloud storage patterns
• Practical experience with IAM configurations, network security protocols, S3 patterns for encryption workflows, and cloud governance frameworks
• Applied technical proficiency with IaC tools such as Terraform;
  Git Hub version control; automated CI/CD pipelines
• Collaborative mindset with excellent communication skills for multidisciplinary team environments