Consultant Chemometrician – Spectral Intelligence; SpecAI & Bacterial

Ready to bring your chemo metric expertise to the frontier of bacterial diagnostics?

We are seeking an experienced chemometrician, ideally based in the Greater Boston/Cambridge area, who can engage 20-40 hours per month (hours vary with project cadence). You will partner closely with our microbiologists, data scientists, and hardware engineers—in-person at The Engine—to design, refine, and validate chemo metric models that underpin bacterial n our SpecAI stack.

This is an independent contractor role.

• Bacterial  Architecture:
• Design and execute supervised and unsupervised chemo metric pipelines (e.g., PLS‑DA, etc.) for rapid discrimination of bacterial species and strains from hyperspectral data.
• Contribute to sample‑prep and data‑acquisition SOPs that maximize spectral information content and reduce confounders (media, growth phase, mixed cultures).
• SpecAI Integration:
• Package chemo metric algorithms for cloud‑native deployment inside SpecAI.
• Med Tech / Regulatory Readiness
• Help define analytical‑performance studies (LoD, specificity, repeatability) aligned with FDA guidelines for IVD instruments.
• Produce clear technical documentation to support design‑history files and 510(k) / de novo pathways.
• Cross‑Functional
  
  Collaboration:
  
  
• Work on site at The Engine most weeks to white‑board with optical engineers, run lab experiments, and coach junior data scientists in chemo metric best practices.
• Present findings to leadership, partners, and occasionally to investors or strategic customers.
• Thought Leadership:
• Author or co‑author conference papers and poster sessions (e.g., SciX, FACSS, Pittcon) to cement Hyper Spectral’s leadership in spectral AI for microbiology.

• Ph.D. or Master’s in Chemometrics, Analytical Chemistry, Applied Statistics, Bioengineering, or related field.
• 5+ years hands‑on building multivariate models for spectroscopic data (VNIR/MIR, Raman, FTIR, hyperspectral imaging).
• Demonstrated success in classifying or quantifying bacterial or microbial signatures (medical diagnostics, food safety, or environmental monitoring).
• Fluency in Python scientific stack (numpy, scikit‑learn, tensor flow/py Torch), plus one of MATLAB or R.
• Comfortable designing experiments and analyzing large data sets in collaboration with wet‑lab microbiologists.
• Able to be physically present at The Engine (Central Square, Cambridge) at least one day most weeks; additional remote availability on short notice.
• Self‑starter who thrives in fast‑moving, sometimes ambiguous start‑up environments and communicates crisply with cross‑disciplinary teams.

• Experience preparing data packages for FDA, CE‑IVDR, or ISO
  13485 submissions.
• Familiarity with embedded ML optimization (Tensor
  
  RT, ONNX, EdgeTPUs).
• Publication record or patents in spectral classification, chemometrics, or AI‑driven diagnostics.
• Prior work with fluorescence or Raman‑based pathogen detection.

• Commitment: ~20 – 40 hours/month, spread flexibly; peaks aligned with lab campaigns and model‑release sprints.
• Location: Hybrid—remote plus regular on‑site at The Engine, Cambridge, MA.
• Compensation: Hourly consulting rate commensurate with expertise; eligibility for future company‑wide incentive plan.
• Start: September 2025 or earlier.

Send your CV, a brief project portfolio, and preferred availability to careers with the subject line "Consultant Chemometrician – Cambridge".

Hyper Spectral Corp is an equal‑opportunity employer and contractor engager. We celebrate diversity and are committed to creating an inclusive environment for all employees and consultants.