DMPK Scientist

ESSENTIAL FUNCTIONS Primary duties/responsibilities

• With guidance, initiates and executes scientific research and experiments and interprets and communicates results as part of multi-disciplinary team(s).
• Performs and maintains established in vitro and in vivo metabolism/bioanalysis assays.
• With guidance, develops new, and improves upon existing DMPK assays.
• Performs hands‑on in vitro and in vivo metabolism/bioanalysis assays using LC‑MS/MS.
• Documents experiment details in lab books, records results in database and prepares study reports.
• Abides by all safety and regulatory guidelines.
• Performs other tasks and assignments as needed or specified by management.
• Contributes to general lab needs such as:
• Equipment maintenance and/or troubleshooting.

• A Master's degree in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or other related scientific discipline and a minimum of 2 years of relevant and progressively responsible experience in a pharmaceutical, biotechnology or similar environment OR a Bachelor's degree in these same disciplines and a minimum of 4 years of the same experience.

• Demonstrated experience in conducting in vitro and in vivo DMPK studies, such as metabolic stability in liver microsomes and hepatocytes, CYP inhibition and induction, and bioanalysis in various matrices etc.
• Demonstrated experience in operating and troubleshooting contemporary LC‑MS instruments and automated liquid handlers.
• Hands‑on experience with liquid handlers, LC‑MS instruments, and other equipment.
• Detailed knowledge of DMPK and applied techniques.
• Experience with developing and optimizing relevant DMPK assays.
• Ability to work independently and collaboratively, as required, in a fast‑paced, matrixed, team environment that may consist of both internal and external team members.
• Proficiency with Microsoft Office.
• Good verbal and written communication skills.
• Analytical thinker with excellent problem‑solving skills and the ability to adapt to changing priorities and deadlines.
• Excellent planning, organization, and time management skills including the ability to support and prioritize multiple projects