Senior Scientist – Process Development

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*
* The Opportunity:

** Avantor is seeking a highly skilled and motivated Senior Scientist to lead and support process development initiatives and manufacturing operations for excipients and reagents.
This role requires deep expertise in chemical engineering principles, mammalian cell culture, and bioreactor-based process development. The successful candidate will play a pivotal role in designing scalable processes, supporting tech transfer, and resolving on-the-floor manufacturing challenges. A Ph.D. in Chemical, Biochemical, or Biomedical Engineering or related field is required.
** What we’re looking for**
* ** Ph.D. in Chemical Engineering, Biochemical Engineering, Biomedical Engineering, or related field** (required).
* Minimum of
** 5+ years
** of industry experience in
** mammalian cell culture-based bioprocess development
** and
** GMP manufacturing support**. Doctoral or relevant academic experience can be counted as equivalent experience to industry experience.
* Strong knowledge of
** bioreactor operations**, including design, scale-up, control strategies, and troubleshooting.
* Proficiency in
** chemical process principles
** such as mixing, heat transfer, and reaction engineering as applied to biologics production.
* Familiarity with
** single-use or multi-use bioreactor systems**, aseptic operations, and automation platforms.
* Excellent problem-solving, technical writing, and cross-functional communication skills.
*
* Preferred Qualifications:

*** Experience with continuous bioprocessing, process modeling, or chemical processing
* Exposure to downstream processing (filtration, chromatography) and integration with upstream.
* Familiarity with ICH, FDA, and EMA guidelines for biologics manufacturing.
* Demonstrated experience with QbD, DoE, and statistical tools (e.g., JMP, Minitab).
** How you will thrive and create an impact
**** Process Development
*** Design, develop, and optimize
** mammalian cell culture processes
** in bench-scale and pilot-scale
** bioreactors**, including fed-batch and perfusion modes.
* Apply
** chemical engineering fundamentals** (mass transfer, kinetics, thermodynamics) to scale up unit operations effectively and predictably.
* Support
** media/feed strategy development**, metabolic analysis, and process parameter optimization for improved productivity and product quality.
* Collaborate with analytical teams to interpret process data, perform root cause analysis, and drive data-based decisions.
* Author technical development reports, risk assessments, and regulatory documentation
** Manufacturing Support
*** Serve as a
** technical subject matter expert (SME)
** during GMP manufacturing campaigns, providing on-the-floor support and troubleshooting.
* Participate in
** deviation investigations**, CAPAs, and change controls related to cell culture and bioprocess equipment.
* Drive
** technology transfer
** of processes from development labs to GMP facilities, ensuring proper documentation, training, and scale-up readiness.
* Support validation activities, including process performance qualification (PPQ) and equipment qualification (IQ/OQ/PQ).
** ENVIRONMENTAL WORKING CONDITIONS & PHYSICAL EFFORT (Under Typical Positions)
** The work environment is a laboratory/office setting, and the appropriate PPE will be required in designated areas. The Senior Scientist may occasionally travel to other Avantor locations or customer sites. This is a full-time position.

The above statements are intended to describe the general nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, skills, efforts or working conditions associated with a job.
** Disclaimer:
** The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Avantor is proud to be an equal opportunity employer.
** Dare to go further in your career.
** Join our global team of 14,000+ associates whose passion for discovery…