Scientist​/Senior Scientist, Cell Biology

At Ambrosia Biosciences, our mission is to develop innovative, orally delivered small‑molecule therapies that address the global challenges of obesity and metabolic disorders. Founded in 2024 and headquartered in Boulder, Colorado, we leverage a world‑class team of scientists to pioneer next‑generation treatments targeting incretins and class B GPCRs. Backed by leading investors, including Merck, BVF Partners, and Boulder Ventures, we are committed to advancing safe, effective, and accessible therapeutics that transform lives worldwide.

As we expand our operations and accelerate our preclinical programs, we seek passionate, driven individuals eager to make a meaningful impact in a dynamic, fast‑paced environment. If you’re ready to contribute to cutting‑edge science with real‑world applications, we invite you to join our team.

Research & Development

Boulder, CO (onsite)

The Cell Biology group at Ambrosia Biosciences is seeking a motivated and skilled scientist to join our team as a Scientist or Senior Scientist. This is a high‑impact, laboratory‑intensive role designed for an enthusiastic scientist eager to grow their career in drug discovery. Working alongside experienced drug hunters, you will focus on GPCR biology, cell‑based assays, and mammalian cell culture to support our discovery programs.

The level of the position will be determined based on the candidate’s education and industry experience.

• Scientist:
  Ph.D. in Cell Biology or closely related field (0–2 years experience), Master’s (3–5 years relevant industry experience), or Bachelor’s degree (5–7 years relevant industry experience).
• Senior Scientist:
  Ph.D. in Cell Biology or closely related field (2–5 years experience), Master’s (5–7 years relevant industry experience), or Bachelor’s degree (7–9 years relevant industry experience).
• Robust expertise in GPCR biology, including GPCR expression, signaling, and functional characterization. Experience applying these capabilities to metabolic disease research is strongly preferred.
• Highly skilled at design and execution of novel cell‑based assays including live‑cell imaging techniques, fluorescence or HTRF‑based assays, and related methodologies for monitoring cellular processes in real time.
• Extensive laboratory experience with mammalian cell culture, qPCR, cell sorting and flow analysis, transfection, Western blotting, and microscopy.
• Proven ability to generate and characterize stable mammalian cell lines.

• Strong interpersonal and collaborative skills. Must be a team player with excellent communication skills—both verbal and written.
• Self‑motivated and adaptable, with a commitment to continuous learning and process improvement.
• Demonstrated ability to stay current with scientific advances, critically assess relevant literature, and quickly integrate emerging concepts and techniques into research projects.
• Proficiency in computer skills essential for scientific research, including Office Suite, statistical analysis (Graph Pad or other), and instrument specific analysis tools (Flow Jo, Incucyte, etc.).

• Scientist: $90,000 – $110,000 annually
• Senior Scientist: $110,000 – $125,000 annually
• Eligible for an annual bonus based on company performance.
• Participation in Ambrosia Biosciences’ stock option plan.
• 401(k) plan with 4% company matching.

Ambrosia Biosciences is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

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