Postdoctoral Associate, Pulmonary Center, Department of Medicine

Postdoctoral Associate, Pulmonary Center, Department of Medicine

Boston University Medical Campus – Postdoctoral

Job Location:

Boston, Massachusetts

Position Type:
Full-Time/Regular

Salary Grade: $67,500.00–$72,000.00

We are recruiting highly motivated Postdoctoral Fellows to work on projects in Immunology and Host-Pathogen Interactions within the Department of Medicine at Boston University. The immune system protects against invading pathogens and opportunistic microbes at barrier surfaces such as the lung and gut. Dysregulation of these interactions plays a critical role in bacterial infections (including pneumonia and sepsis) as well as inflammatory bowel disease.

In the absence of fully effective therapeutic options, these microbe-driven inflammatory diseases represent a major and growing burden on health care systems worldwide.

Our laboratory is dedicated to achieving a mechanistic understanding of the molecular pathogenesis of bacterial infections and host‑pathogen interactions, with the goal of identifying and evaluating novel therapeutic targets. A particular emphasis is placed on novel genes, for which our laboratory has generated multiple genetically engineered mouse models. Projects may focus on IBD‑related mucosal immunity or on pneumonia and sepsis, or on shared immune mechanisms across these disease contexts.

• Bacterial polyphosphates in immunity at barrier organs (gut and lung)
• Host‑pathogen interactions
• Innate immune cells, including macrophages, neutrophils and T cells
• Cytokine biology and immune signaling pathways (e.g. G‑protein signaling)

Pathogens of interest include Escherichia coli, Streptococcus pneumoniae, Legionella spp., and others. Projects will be individually tailored to align with the qualifications and scientific interests of the postdoctoral fellow.

The research environment offers access to a broad spectrum of state‑of‑the‑art immunological techniques, including single‑cell transcriptomics (scRNA‑Seq, TOTAL‑Seq) and phospho‑/proteomics. Data analysis is supported by an experienced bioinformatician within the laboratory.

Preferred candidates will have prior experience in experimental immunology, mouse models of infection or inflammation, innate immunity, and/or transcriptomic or proteomic approaches.

Please send your CV, publication list, transcripts and names of three references to:
Markus Bosmann (mbosmann), M.D., Associate Professor of Medicine, Pathology & Laboratory Medicine, Investigator of the National Emerging Infectious Diseases Laboratories.

We are an equal‑opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, natural or protective hairstyle, religion, sex, age, national origin, physical or mental disability, sexual orientation, gender identity, genetic information, military service, pregnancy or pregnancy‑related condition, or because of marital, parental, or veteran status. We are a VEVRAA Federal Contractor.

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