Research Lab Technician

Site:
The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

In the Nakashima Lab at the Harvey Cushing Neuro-Oncology Laboratories, within the Department of Neurosurgery at Brigham and Women's Hospital, our research is focused on developmental immunotherapy with tumor-permissive oncolytic viruses and tumor immune mechanisms governing highly immune tolerance and resistance in brain tumors. We use advanced DNA manipulation and animal models in conjunction with the latest molecular and immunological tools in our investigation of brain tumor and immunity.

We are looking for an energetic and highly organized research assistant interested in various biological and immunological experiments, including plasmid DNA, RNA, genome extraction, (RT-)PCR, Western blot, immunohistochemistry, flow cytometry, virus, cell culture, and other essential molecular biological experiments.

• Bachelor’s degree in biology, veterinary, neuroscience, immunology, or related field.
• Basic knowledge and experience with techniques of cell culture, tissue processing, molecular biology, chemistry, small animal handling and colony management skills a plus.
• Good laboratory practices, well organized in planning and performing lab work, maintaining good lab records and electronic notebooks are necessary.
• Strong motivation for curiosity-driven research, hypothesis-generation, and constant desire to improve on scientific technologies.
• Additional experience working in research labs or animal facilities that handle mice experience helpful;
  Experience with biological and immunological laboratory techniques including DNA cloning into vectors, virus propagation and titration, processing methods and analysis of DNA/RNA/protein from cells, tissues and mice, tissue culture, operations of fluorescent microscopy, flow cytometry, PCR machines, and/or ultra-centrifugation is a plus.
• Excellent oral and written communication skills. Ability to communicate effectively with a diverse team of researchers.
• Ability to make at least 1-year commitment to the position to contribute technically to newly funded NIH grant studies. Longer term contribution of more than 1 year is welcomed.

• Working with Dr. Nakashima and team to conduct research projects.
• Contributing technically to the existing funded NIH grant studies and collect data for submission of the NIH grant proposal.
• Assisting with mouse studies, including colony maintenance, health monitoring, and in vivo imaging and post-surgery monitoring.
• Maintaining biological material resources.
• Documenting all research activities using a digital notebook (Lab Archives).
• Making pre-experiment lab preparations (e.g., autoclave, reagent preparation, etc.).
• Attendance at all lab meetings.
• Maintaining lab equipment.

This position is grant funded. Due to the nature of experimental protocols, some off-hours work may occasionally be required.

Remote Type:
Onsite

Work Location:

60 Fenwood Road
Scheduled Weekly

Hours:

40
Employee Type:
Regular

Work Shift:

Day (United States of America)
Pay Range: $20.16 - $29.01/Hourly
Grade: 5

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at .