Research Lab Tech Lead Research Neurology VK

Summary

Carries out broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of research unit. Helps onboard new staff and train them in the lab.

Does this position require Patient Care? No

• Independently performs non-routine, highly specialized experimental procedures.
• Participates in the design and modification of research protocols.
• Develops research methodologies within the parameters of experimental protocols and research objectives.
• Composes and may present sections of research reports and manuscripts.
• Performs advanced data analysis using advanced statistical techniques.
• Responsible for the oversight and coordination of lab activities, including quality assurance.
• Responsible for the oversight and coordination of the scheduling of all procedures.
• Responsible for troubleshooting problems and instructing others in highly specialized techniques.

We are seeking a motivated and detail‑orientated Lead Research Lab Tech to join the Genomics Platform at The Gene Lay Institute of Immunology and Inflammation of Brigham and Woman's Hospital, Massachusetts General Hospital, and Harvard Medical School. The Institute aims to understand the immunologic mechanisms behind inflammatory diseases, cancer, and aging with the ultimate goal of identifying novel therapeutic targets. The Genomics Platform offers a range of next generation sequencing and spatial omics technologies and services, and utilizes state of the art robotics systems and the latest technologies and methods to generate high-quality, comprehensive genomics data.

This position will work closely with the Platform Manager, Project Manager, and Data Manager to assist in data generation and processing, as well as maintain laboratory equipment and support experimental workflows. Looking for an applicant with molecular biology experience and strong organizational skills/attention to detail. This position will directly interface with researchers and requires strong communication skills. This position involves extensive training at the initial stage, and hence requires a two‑year commitment minimum.

• Bachelor's Degree Related Field of Study required

• Previous Research Lab Experience 3-5 years required
• Excellent interpersonal and collaborative skills preferred
• Ability to work independently and as part of a team preferred

• Organize and maintain a functioning research laboratory.
• Troubleshoot scientific and non‑scientific problems.
• Proficiency in Word, PowerPoint, Excel, and Internet searches is preferred.
• Well‑versed in laboratory standards and practices.
• May teach moderately difficult‑to‑complex lab techniques to students and research personnel.
• May provide functional guidance to lower level technical personnel.
• High degree of computer literacy preferred.
• Sound analytical and organization skills preferred.
• Good oral and written communication skills preferred.
• Must be able to logically and effectively structure tasks and set priorities preferred.

• Under supervision of or assisting the Platform Manager, provide next generation sequencing and spatial transcriptomics services, including single cell and bulk RNA‑sequencing library preparation, spatial omics, and other workflows as needed.
• Carefully maintain records/logs of Genomics Platform projects. This includes sample tracking, archiving, and storage.
• After proper training, perform sectioning, staining, and histology quality control for spatial omics projects.
• Perform in vitro and in vivo experiments run by the Genomics Platform.
• Maintain all equipment within the Platform to keep them in good working order. Work with vendors to schedule preventative maintenance visits and coordinate all repairs needed for the equipment.
• Track inventory, order supplies, receive and log orders to maintain adequate stock of Genomics Platform consumables.
• Serve as the emergency response personnel required to respond to…