Scientist​/Scientist II, Translational Medicine

About Jade Biosciences

Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade's lead candidate, JADE
101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade's pipeline also includes JADE
201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE
301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit  and follow the Company on Linked In.

Role Overview

The Research & Translational Medicine group at Jade is looking to add a Scientist/Scientist II to our team. The Scientist, Translational Medicine will develop, validate, and implement bioanalytical and biomarker assays to support Jade's preclinical and clinical programs.. This is an exciting opportunity to join a growing team, develop your skills and experience, and develop great professional relationships in a fast-paced environment.

This is a fully remote role and will require occasional travel.

Key Responsibilities

• Design, develop, and optimize bioanalytical and biomarker assays to assess drug potency, mechanism of action, and functional activity across preclinical and clinical programs.
• Select, qualify, and manage CRO partners for bioassay and biomarker development, transfer, and analysis, ensuring seamless execution, alignment on timelines, budgets, and quality expectations.
• Conduct detailed review and analysis of bioanalytical and biomarker data, ensuring rigorous scientific validity and compliance with regulatory standards.
• Collaborate with clinical and regulatory teams to draft, review, and finalize bioanalytical and biomarker sections of clinical protocols, investigator brochures, and regulatory submissions (e.g., IND, BLA), ensuring scientific accuracy and compliance with applicable guidelines.

Qualifications

• Scientist level:
  Ph.D. in a relevant scientific discipline with 0-3+ years of experience, M.S. with 8+ years, or B.S. with 10+ years in bioanalytical or biomarker assay development. Scientist II level:
  Ph.D. in a relevant scientific discipline with 3-5+ years of experience, M.S. with 10+ years, or B.S. with 12+ years in bioanalytical or biomarker assay development.
• Proven experience managing sample analysis for global clinical trials and interfacing with regulatory authorities.
• Demonstrated ability to manage CROs, including contracting, study design, and technical oversight.
• Strong laboratory and project management skills, with expertise in critical thinking and scientific problem-solving.
• Hands-on experience with diverse assay platforms (e.g., flow cytometry, immunohistochemistry, ELISA, Luminex, MSD).
• Solid understanding of drug development processes and regulatory requirements.
• Excellent analytical, written, and oral communication skills, with strong interpersonal abilities.
• Highly motivated, detail-oriented, and curious, with a creative approach to scientific challenges.
• Ability to travel for company meetings and scientific conferences as needed.

Position Location

This is a remote role; periodic travel to team and company events is required.

The anticipated salary range for candidates for this role at the Scientist level is $115,000 - $130,000 and at the Scientist II level $130,000 - $145,000. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.

As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.

Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.

Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.