Scientist, Biologics Cell Line Development

Our mission at Asimov is to radically advance humankind's ability to design living

systems. We're developing a mammalian synthetic biology platform--from cells to

software--to enable biotechnologies with outsized impact, with an initial focus on

gene therapies, cell therapies, and protein therapeutics.

We are seeking a Scientist, Biologics Cell Line Development to join our team in

Boston, MA and help push the boundaries of biotherapeutic cell line development.

This role is for a hands-on technical leader on our team, who will drive CHO-based

cell line development for biologic therapeutics while helping advance scalable,

automated and data-driven CLD workflows. You will design and execute complex

experimental strategies, improve CLD workflows and systems, coordinate project

efforts, and mentor junior scientists.

The successful candidate will also work closely with Asimov's synthetic biology and

process development teams. This is a unique opportunity to work at a nimble,

forward-thinking synthetic biology startup and help build the future of biological

engineering.

About the Role:

* You'll perform all aspects of CHO cell line engineering for production of

therapeutic candidates including transfection, cloning, characterization, and

cell banking using state-of-the-art equipment.

* Design, execute, and optimize high-throughput and/or automated CLD

workflows, including integration of new tools, instrumentation, or data

streams.

* You'll drive innovation through the development of improved host cells,

expression vectors and cell line development workflows.

* You'll identify emerging practices for biologics cell line development and

manufacturing to shape scientific strategies and develop improved CHO

expression systems.

* You'll represent the cell line development team on cross-functional projects,

making decisions for cell line activities and effectively communicating

results, progress and plans.

About You:

* You have a Ph.D. in Biological Engineering, Cell Biology, Molecular Biology,

or a related field.

* You have experience performing biological drug production, protein

analytics and/or process development

* We're looking for someone with 1-3 years of hands-on industry experience

performing CHO cell line development in support of biologic (mAb & bsAb)

therapies.

* You're a creative problem solver and get excited about the opportunity to

drive the creation of industry-disruptive technology.

* Experience working with automation, high-throughput screening, or scaled

CLD workflows, such as liquid handling systems, automated

cloning/screening platforms, or bioreactor systems.

* Don't let this stop you from applying, but it's a plus if you are familiar with

ambr
15 and or ambr
250 systems.

* Experience working with a global customer base isn't a requirement for this

role but bonus points if you have it.

We're fueled by a vision to transform biological engineering into a fully fledged

engineering discipline. Should you join our team, you will grow with a constantly

evolving organization and push the frontiers of synthetic biology. Company culture

is key to Asimov, and we believe that our mission can only be achieved by bringing