Research Scientist

Overview

Vertex Pharmaceuticals is seeking a Research Scientist to join the Analytical Development, Cell and Gene Therapy group. This position is expected to serve as a key contributor in expanding our capabilities for supporting drug substance and drug product program development, and extensive hands-on experience with cell therapies is preferred. The scientist will support method development and troubleshooting, as well as author and review method documents, analytical study protocols, and reports.

The scientist will collaborate closely with research, process development, manufacturing, regulatory, and quality to develop and innovate Cell and Gene Therapy products.

• Designs and executes cellular and molecular assays to support stability efforts for cell therapy products
• Provide expertise in experimental design, data analysis, assay trouble shooting, technical report writing, and presentations
• Maintain proper documentation of experimental results and data interpretations
• Ensure data quality and maintain data integrity of analytical results to support decision making
• Independently prepares study presentations and presents experimental conclusions at internal team meetings
• Collaborate with research and process development teams to develop fit for purpose analytical characterization methods for target optimization, product characterization and product investigations

• Strong hands-on experience with organoid tissue culture (or tissue engineering), perfusion systems, and molecular assays is required
• Prior experience in analytical development, particularly cellular drug product stability, is required
• Prior experience with tissue culture media formulation is preferred
• Prior experience with stem cells, T1D, and/or pancreatic islet biology is preferred
• Demonstrated capabilities to independently digest and formulate experimental conclusions by referencing orthogonal analytical results
• Ability to use information gained from experiments to inform method and program decisions
• Skilled in efficient study design and demonstrated expertise in writing SOPs, analytical protocols and reports
• Ability to multi-task as necessary, managing competing priorities, and advancing multiple projects within required timelines
• Demonstrated ability to work cross-functionally to improve communication, strong track record in cross-team collaboration
• Strong oral & written communication skills

• D. (or equivalent degree) and +1 years of relevant post-doctoral employment experience, or
• Masters Degree (or equivalent degree) and 5-7 years of relevant employment experience

• This is an onsite position at our Boston LC1 site and occasional travel to Boston FP site
• Able to work upright and stationary and/or standing for typical working hours
• Able to use and learn standard office equipment and technology with proficiency
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities
• Some evening and weekend work should be expected

6 months with the chance to extend

$60/hr.

-$70/hr.

Monday-Friday. Weekend flexibility required

This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third- party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer.

The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements

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