Senior Research Associate, Functional Biology

Senior Research Associate, Functional Biology

Ampersand Biomedicines is a Flagship Pioneering company creating better medicines that work precisely where needed in the body and nowhere else. We are building a pioneering team that shares a drive to make a difference and works well in a fast‑paced, highly collaborative environment. Every employee has the opportunity to learn about cutting‑edge innovations, take chances, support colleagues, and share ideas.

We are seeking a highly motivated biologist with a strong background in cell/molecular biology to contribute to projects focused on the discovery and development of protein therapeutics. The role focuses on cell‑based and ex‑vivo approaches to designing and understanding our biologic therapeutics.

As a member of our team, you will execute experiments to characterize activity, mechanism of action, and therapeutic potential of early‑stage biologics, contributing to multiple projects across the Ampersand pipeline. This on‑site, lab‑based role is located in South Boston with a planned move to Watertown in 2026.

• Support discovery programs through development and execution of screening/mechanistic/functional assays focused on activity of multi‑specific antibodies to advance candidate therapeutics across various disease targets.
• Work independently on experimental design, execution, interpretation, and presentation of results to validate hypotheses related to project needs.
• Read and adapt scientific literature and internal protocols to accomplish assignments, demonstrating broad, versatile technical expertise and problem‑solving. Implement and innovate new protocols/techniques as needed.
• Collaborate with biology and multidisciplinary teams for cross‑functional coordination.
• Compile and document experimental data; manage electronic laboratory notebook and centralized databases for diligent record keeping.
• Impact projects primarily through lab‑based activities.

• Bachelor’s or Master’s degree in Biological Science or related field with 2+ years of hands‑on experience in biotech or pharma.
• Excellent skills in primary cell culture (sterile technique, handling challenging cell types), stable and transient protein expression, fluorescence/luminescence‑based assays, and flow cytometry in a medium to high‑throughput setting.
• Expertise in disease areas including immunology, metabolism, and fibrosis is a plus.
• Familiarity with Flow Jo, Incucyte software, ELN, and Prism is a plus.
• Excellent written and verbal communication skills to effectively present results and scientific data to team leaders and cross‑functional teams.
• Ability to learn new skills and apply them in a fast‑paced environment with flexibility to manage changing timelines.
• Enthusiastic about playing a pivotal role in the dynamic, multidisciplinary environment of a small biotech.

Ampersand Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status.

The salary range for this role is $81,000 - $107,300. Compensation will depend on qualifications, skills, competencies, and experience. Ampersand offers healthcare coverage, an annual incentive program, retirement benefits, and other benefits.