Human Resources Business Partner Senior Director; Cell & Genetic Research Site

Position: Human Resources Business Partner Senior Director (Cell & Genetic Research Site)
** Job Description
**** General

Summary:

** We are seeking a strategic, influential, and visionary
** HR Business Partner Senior Director
** to lead talent strategies for Vertex’s Cell & Genetic Therapies Research site and Research organizations during a transformative era of scientific innovation and organizational growth. This role will serve as atrusted advisor to Research Senior Vice Presidents and Vice Presidents and their leadership teams**,
** shaping organizational design, culture, and workforce strategies that enable cutting-edge discovery and long-term scientific success. Reporting to the Lead HRBP for the Chief Scientific and Global Research organization, this individual will sit on Research leadership teams and play a critical role in driving enterprise-wide HR initiatives and change leadership.

As the primary site HRBP for the Jeffrey Leiden Center for Biologics, Cell & Genetic therapies, the Senior Director will provide and ensure the delivery of HR programs and services including leader coaching and consultation, talent development and succession planning, talent acquisition of key positions, employee experience and engagement, and compensation processes.
** Key

Duties and Responsibilities:

*** Lead strategic HR initiatives across multiple Research domains (Discovery Biology, Chemistry, Translational Research, Computational Sciences) and influence cross-functional areas such as Data Science and Platform Technologies.
* Serve as a key architect of organizational design and transformation, advising senior leaders on complex change management and culture evolution strategies.
* Drive enterprise-level workforce planning, including capability mapping, succession planning, and talent acquisition strategies aligned with Vertex’s long-range scientific roadmap.
* Leverage advanced analytics and insights to inform strategic decisions, challenge assumptions, and demonstrate measurable impact on scientific and organizational outcomes.
* Influence and shape HR strategy at the sub-function level, ensuring alignment with corporate priorities and Research objectives.
* Build and maintain deep partnerships with HR Centers of Excellence (Total Rewards, Talent Management, People Experience, Strategic Analytics).
* Represent HR on Research leadership forums, contributing to strategic planning and decision-making for the sub-function.
* Ensure flawless execution of critical HR processes (performance management, compensation planning, leadership development) while driving continuous improvement and innovation.
** Knowledge and

Skills:

*** Recognized expert in HR strategy and organizational effectiveness, with proven ability to influence senior executives and shape sub-functional priorities.
* Deep understanding of scientific environments, including cell and gene therapy, and workforce capability needs for discovery and translational research.
* Advanced proficiency in change leadership, culture transformation, and strategic workforce planning.
* Strong business acumen and ability to translate HR strategies into measurable business outcomes.
* Exceptional communication and influencing skills; ability to negotiate and shape opinions of senior leaders.
* Expertise in leveraging data-driven insights and storytelling to inform decisions and drive transformation.
*
* Education and Experience:

*** Bachelor’s degree in Human Resources or related discipline, or equivalent professional experience.
* Typically requires 12+ years of progressive HR experience, including significant leadership responsibility and experience in complex, multi-site scientific organizations.
* Demonstrated success in leading through subordinate managers and influencing sub-function strategy.
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** Pay Range:**$227,200 - $340,800
** Disclosure Statement:
** The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies,…