Boston, MA ; Cambridge, MA Senior Director, Strategy and Operations

Senior Director, Strategy and Operations

Boston, MA USA;
Cambridge, MA USA

Flagship Pioneering is a company that creates companies, building ground-breaking platforms that change the world. We are a brave and bold organization of creative-thinkerswith insurgent mindsetsand corporate-builders withincumbent expertise. Our mission is to create, launch, and scale breakthrough ventures that transform how we live, work, and connect, using AI to accelerate technology breakthroughs.

Join Flagship Pioneering, an industry leader in life sciences venture creation, as a Senior Director driving strategy, operations, and management of pioneering companies. This role works closely with Flagship’s executives to translate vision into operational excellence and manage the growth and integration of early- and mid-stage companies in the life sciences sector.

Join Flagship Pioneering, an industry leader in life sciences venture creation, as a Senior Director driving strategy, operations, and management of pioneering companies. This role offers a blend of responsibilities working closely with Flagship’s executives to translate vision into operational excellence and manage the growth and integration of early- and mid-stage companies in the life sciences sector.

• Strategic and Operational Leadership: Act as a strategic partner to key leaders, reporting to the Origination Business Unit (OBU) head, building and refining internal systems to drive organizational excellence and foster cross-functional collaboration.
• Portfolio and Business Unit Management: Work directly with OBU leadership to execute operational plans, ensuring that all functional needs are met, and drive enterprise-wide initiatives that align with organizational objectives.
• Planning and Integration: Lead the planning, integration, and operational management of multiple early and mid-stage companies, ensuring consistent implementation of processes and driving New Co to Growth Co transitions across the OBU.
• Financial Planning and Resource Allocation: Own budget and financial planning processes, guide resource allocation across portfolios, and track value accretion relative to time and resource allocation.
• Governance and Knowledge Sharing: Establish governance mechanisms and cross-company knowledge sharing platforms to improve team-level systems and strategic science insights.
• Complex Initiative Management: Drive complex, cross-functional initiatives through ambiguity and change, setting a standard of excellence in project management and operational rigor.

• Bachelor’s degree required; advanced degree (MBA, MS, Ph.D.) preferred.
• 5-10+ years of experience in entrepreneurial executive operations, project management, or strategy consulting within the life sciences sector.
• Strong financial literacy, strategic mindset, and experience in driving complex initiatives.
• Excellent leadership, team building, and communication skills.

• Proven ability in deploying AI-enabled solutions to amplify core operating functions.
• Ability to frame complex business problems creatively and influence senior leaders.
• Strong presentation skills with the ability to deliver insights effectively to senior leaders.
• Collaborative work with cross-functional teams and external partners.
• Ability to adapt to changing conditions and drive results across multiple simultaneous deliverables.

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, and twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.