Executive Director, Clinical Operations Program Management; CVRM

Job Title:

Executive Director, Clinical Operations Program Management (CVRM)

Possible Locations: Gaithersburg, MD or Boston, MA | Bio Pharma R&D

About the role: We are seeking a motivated, collaborative, data‑driven enterprise leader to shape and deliver the Cardiovascular, Renal & Metabolic (CVRM) clinical operations portfolio. As Executive Director, Clinical Operations Program Management, you will lead Senior/Global Program Directors across early and late development, translate CVRM strategy into clear operational objectives, and drive disciplined, insight‑led decision‑making to deliver trials to time, quality, and cost.

• Leadership and People
  • Functional leadership
    : line‑manage and develop Program Management Senior Directors; recruit, resource plan, and build capabilities.
  • Coaching and culture
    : mentor teams, champion new ways of working, foster collaboration, accountability, and continuous improvement.
• Portfolio Strategy and Delivery
  • Strategy translation
    : convert CVRM strategy into forward‑looking clinical operations objectives across early and late programs.
  • Operational excellence
    : ensure robust strategic and operational planning; lead operational planning reviews; secure successful asset transitions from CDID to Phase III.
  • Performance
    : deliver portfolio to time, quality, and cost; proactively identify trends, risks, and opportunities using internal and external data.
• Cross‑Functional Influence and Governance
  • Enterprise impact
    : represent Clinical Operations at governance and decision bodies (e.g., DRC, PRC); serve on Steering Committees and cross‑functional initiatives.
  • Best practices
    : drive clarity and consistency across strategic processes; establish standards for trial delivery; share lessons learned across TAs.
• Advanced Analytics and Innovation
  • Insight‑driven recommendations
    : conduct rigorous analyses to inform resourcing and delivery optimization; provide clear, actionable guidance to leadership.
  • AI enablement
    : leverage AI and advanced analytics to enhance efficiency of clinical operations resources and decision quality.
• External Engagement
  • Partnerships
    : engage AROs, CROs, labs, KEEs, and development partners; represent Clinical Operations at congresses, investigator meetings, and with health authorities.

• Education
  :
  Bachelor’s/Master’s in a related discipline; advanced degree preferred.
• Experience
  : extensive global drug development leadership across early and late phase; significant program management with complex projects (resourcing, financials, business cases).
• Expertise
  : strong understanding of complex study design, TPPs, CDPs, competitive dynamics, pricing, market access, and global regulatory environments.
• Skills
  : strategic influencing, clear and organized thinking, financial evaluation of assets/brands, business planning, high‑impact communication and presentation.
• Leadership
  : proven ability to lead, mentor, and develop diverse high‑performing teams; collaborate across disciplines; plan, prioritize, and deliver.
• Digital
  : comfortable utilizing AI for ethical, accurate data analyses.
• Travel
  : willingness for domestic and international travel.

• Process transformation
  : driving efficiency and implementing new ways of working.
• Regulatory
  : submission experience; insights from Japan and China delivery.
• Change leadership
  : leading teams through change; clinical environment insight.

This role sits on the CVRM Clinical Operations Leadership Team and the Bio Pharmaceuticals Clinical Operations Extended Leaders Community, shaping strategy and execution across a high‑visibility portfolio that advances patient outcomes globally.

If you’re a strategic, insight‑driven leader who thrives on complex portfolio delivery and cross‑functional influence, we invite you to apply and help transform CVRM clinical operations.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not…