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Associate Director, Statistical Programmer

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Connect Life Sciences
Full Time position
Listed on 2026-03-01
Job specializations:
  • IT/Tech
    Data Analyst, Data Scientist, Data Science Manager, Data Security
Salary/Wage Range or Industry Benchmark: 100000 - 125000 USD Yearly USD 100000.00 125000.00 YEAR
Job Description & How to Apply Below

Responsibilities

  • Lead statistical programming activities across multiple studies or an entire clinical program, ensuring timely, accurate, and submission‑ready deliverables
  • Provide oversight of vendor‑produced SDTM, ADaM, and TLFs, ensuring technical quality, consistency, and regulatory compliance
  • Collaborate closely with internal study teams and external partners to align on timelines, priorities, and quality expectations
  • Oversee CRO deliverables, ensuring clear documentation, traceability, and adherence to standards
  • Develop, validate, and maintain SDTM and ADaM datasets and TLFs to support data review, CSRs, annual reports, publications, and ad hoc data requests
  • Serve as a programming subject‑matter expert for regulatory submissions (e.g., FDA, EMA), including support of electronic submission standards (eCTD)
  • Coordinate and manage data transfers and delivery of required outputs as a lead or supporting programmer
  • Review and contribute to key clinical and regulatory documents
  • Manage multiple priorities, proactively troubleshoot technical and project issues, and contribute to process and infrastructure improvements within the department
  • Evaluate and implement innovative tools and programming technologies to improve efficiency, quality, and scalability
  • Stay current with industry trends, best practices, and emerging technologies in statistical programming and data analysis
Qualifications
  • MS (or equivalent) in Statistics, Biostatistics, Computer Science, or a related field
  • 10+ years of statistical programming experience in the pharmaceutical or biotechnology industry, including support of late‑phase (Phase II/III) clinical trials
  • Proven experience overseeing CROs and external vendors, with accountability for quality, timelines, and deliverables
  • Deep hands‑on expertise with CDISC standards (SDTM, ADaM) and strong knowledge of regulatory submission requirements (e.g., NDA/MAA)
  • Demonstrated ability to independently deliver high‑quality analysis datasets and TLFs for both planned analyses and ad hoc data requests
  • Strong expertise in efficacy endpoint programming and analysis, with the ability to translate clinical objectives into analysis‑ready datasets and meaningful outputs
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Position Requirements
10+ Years work experience
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