Principal ADS Program Lead

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A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across Development  Analytical Data Science teams are mobilized across the portfolio to generate data-driven insights, identify opportunities for scale, and implement impactful solutions. PDD Analytical Data Science is recognized as a leading hub for top industry talent, operating as an agile workforce to deliver regulatory commitments across the portfolio.

We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development.

• You define and drive the programming and analytical strategy across one or more clinical studies, ensuring alignment with clinical and regulatory objectives, accountable to the TA lead.
• You ensure compliance and inspection readiness by establishing robust quality review processes, maintaining thorough documentation, and proactively addressing potential risks to support internal audits and global health authority inspections.
• You drive and uphold data and programming standards by championing the consistent application of standardized methodologies, tools, and code libraries to ensure efficiency, reproducibility, and alignment with enterprise-wide data strategy and regulatory expectations.
• You lead cross-functional planning and execution of data and analytical deliverables, proactively anticipating risks and developing mitigation strategies to ensure quality, consistency, and timeliness.
• You act as a subject matter expert and best practices resource within programming, contributing to the development and refinement of functional standards, tools, and processes.
• You participate in global or complex initiatives, bringing analytical and programming expertise to solve problems spanning studies or functions.
• You contribute to the implementation of innovative approaches, including automation or new delivery models, to enhance efficiency and scalability.
• You collaborate with stakeholders across PDD, such as Biostatistics, Data Management, and Early Development Biometrics, to integrate analytical strategies into development plans and ensure alignment across the end-to-end drug development lifecycle.
• You share knowledge and lessons learned across programs and therapeutic areas to promote continuous improvement, cross-team knowledge transfer, and enhance consistency in analytical approaches.
• You serve as a mentor to less experienced colleagues, promoting best practices in software development, analytics tooling, and scientific collaboration.

• You hold an advanced degree (Master’s or PhD) in Data Science, Statistics, Computer Science, Biomedical Informatics, or a related field.
• You have a minimum of 6 years of experience in pharmaceutical R&D or a regulated environment, with significant exposure to clinical development.
• You have demonstrated leadership of molecule-level analytical strategy or delivery across multiple studies.
• You bring strong technical expertise in statistical programming (e.g., R, SAS), QC practices, and regulatory data standards (e.g., CDISC, ADaM, SDTM).
• You have a proven ability to manage complex timelines, collaborate across functions, and communicate analytical strategies effectively.
• You have experience in vendor oversight and working in matrixed, cross-functional global teams.
• You demonstrate capacity for independent thinking and ability to make decisions based upon sound principles.
• You bring excellent strategic agility including problem-solving and critical thinking skills, and agility that extends beyond the technical domain.
• You demonstrate respect for cultural…