Postdoctoral Research Fellow - D'Andrea Lab

The D'Andrea lab is hiring a Postdoctoral Research Fellow to investigate chromosome instability and susceptibility to cancer. Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells and the impact of germline and somatic mutations on genomic stability, ionizing radiation sensitivity, and defective cell cycle checkpoints. This role focuses on the molecular basis of genomic stability and DNA repair mechanisms in human cancers in a cutting‑edge research environment with advanced molecular biology tools and technologies.

• Design and conduct experiments related to DNA repair pathways, replication fork stability, and ubiquitin signaling.
• Use advanced techniques such as CRISPR/Cas9 gene editing, protein biochemistry, mass spectrometry, and live‑cell imaging.
• Analyze data, interpret results, and present findings at internal and external scientific meetings.
• Collaborate with multidisciplinary teams, including medicinal chemists and clinical researchers.
• Contribute to manuscript writing and grant applications.
• Mentor junior team members and contribute to the overall research environment.

• PhD or MD in Molecular Biology, Cell Biology, Biochemistry, Genetics, or a related field.
• Strong background in DNA repair, cancer biology, or chromatin biology is preferred.
• Experience with mammalian cell culture, protein purification, and molecular cloning.
• Excellent communication skills and ability to work both independently and in a team‑oriented environment.
• Demonstrated ability to publish in peer‑reviewed journals.

Pay Transparency Statement

The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.

For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).

$72,000 - $76,385

At Dana‑Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we.

If working in this kind of organization inspires you, we encourage you to apply.

Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.