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Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing Operations

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Vertex Pharmaceuticals Incorporated
Full Time position
Listed on 2025-12-03
Job specializations:
  • Finance & Banking
    Financial Manager, Corporate Finance, CFO, VP/Director of Finance
Salary/Wage Range or Industry Benchmark: 182400 - 273600 USD Yearly USD 182400.00 273600.00 YEAR
Job Description & How to Apply Below

Job Description

The Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing Operations (BSMO) is a key member of Vertex's Financial Planning & Analysis team. This role will partner closely with Commercial Manufacturing and Tech Ops (CMTO), Commercial Finance and Disease Strategy Team (DST) Finance in support of our Cell and Gene Therapies portfolio, with a specific focus on CASGEVY, the first-ever approved CRISPR-based gene-editing therapy used to treat Sickle Cell Disease and Transfusion-Dependent Thalassemia.

This role will have the opportunity to work across the organization by providing analysis and insights that will drive key decisions around manufacturing strategy and resource allocation in order to optimize the profitability of CASGEVY. In addition, this position will be an integral part of the BSMO Finance team and play a key role in support of P&L, Capital and Inventory budgeting, forecasting, long range planning, and month-end close processes.

This position is based in our Boston, MA location (Seaport area) and requires a hybrid work schedule with 3 days in office /2 days remote on a weekly basis.

Key

Duties & Responsibilities
  • Partners with the External Manufacturing, Supply Chain, and Commercial functions to influence CASGEVY business operations and optimize decisions as part of the Sales and Operations Planning (S&OP) process.
  • Identifies ROI/trade-off opportunities to drive profitability and support key decisions around CASGEVY manufacturing and supply chain strategy.
  • Oversees the monthly/quarterly accounting close for expenses and accruals related to CASGEVY Operating Expense and COGS, including flux analysis and compliance with SOX control requirements.
  • Supports analytics and transparent reporting to drive forecast accuracy and inform on key drivers of any variances to plan, with full transparency on any judgments about risks and opportunities for both operating expenses, capital expenses and COGS.
  • Supports the financial planning process (annual budget, forecasts, long range plan, etc.) by providing forward-looking observations and developing key scenarios.
  • Develops and coaches team members to encourage growth and new opportunities and contributes to an atmosphere of inclusivity across the team.
  • Works closely with other members of the CFO organization including Commercial Finance, DST Finance, Strategic Sourcing and Accounting to maintain a continuous improvement mindset and promote strong communication, sharing of best practices and efficient processes.
Basic Requirements
  • Bachelor's degree in Finance or Accounting required. MBA and/or other advanced degree preferred.
  • 10+ years of relevant experience in finance managerial role, demonstrating strong technical and analytical skills and a track record of success working in a team-based environment or the equivalent combination of education and experience.
  • Experience in business partnering with Manufacturing/Supply Chain executive teams.
  • Proven ability to proactively manage efficient processes across Operating Expenses, Inventory and COGS, driving high-quality inputs from the business in support of creating and managing complex budgets, forecasts, and analyses in a dynamic, fast-paced environment.
  • Deep understanding of Biotech/Pharma manufacturing finance to address a broad range of challenges and business issues across all functions with the ability to make and facilitate quick decisions.
  • Expert analytical and financial modeling skills to evaluate a broad range of financial questions.
  • Excellent communication and presentation skills, with a proven ability to present complex financial insights to senior stakeholders.
Knowledge and Skills
  • Strategic thinking and problem-solving.
  • Critically, this role requires an expert ability to influence without authority at the highest level and collaborate effectively in support of shared goals.
  • Strong business acumen and judgment, and knowledge of the company's markets/products and industry trends.
  • Expertise with Excel and PowerPoint;
    Working knowledge of Hyperion or similar enterprise planning tools.
  • Exceptional interpersonal, written, and verbal communication skills.
  • Ability to lead and drive change in an evolving business environment, coordinating processes involving large numbers of people, complex systems, and tight deadlines to deliver innovative solutions.
  • Demonstrated ability to lead and collaborate cross-functionally, sharing insights and translating learnings into actionable business initiatives whilst partnering to ensure timely execution of project plans.
  • Proactive, organized, and comfortable managing shifting priorities in a rapidly changing environment.
  • Leads with a continuous improvement mindset, with flexibility and ability to adapt to change.
Pay Range

$182,400 - $273,600

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity…

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