Research Associate II - Pathology

Overview

Join the HJF Team! HJF is seeking a Research Associate II to perform research and/or development in collaboration with other scientific and technical staff. May exercise technical discretion in the design, execution, and interpretation of experiments that contribute to project strategies. This position supports the department of Pathology at the Uniformed Services University in Bethesda, MD as part of the Upadhyay laboratory.

The Upadhyay lab studies novel biologics, targeted therapies using in vivo, in vitro, and bioinformatic approaches. They use multiple in vivo and in vitro approaches for activating stress responsive signaling pathways in mammalian cells and murine models, high throughput and single cell sequencing strategies for defining the treatment for cancer including breast and pancreatic cancer.

• Performs complex data analysis and interpretation, verifies and corrects data entry.
• Performs complex laboratory tests, determinations, and analyses involving multiple procedures and a variety of technical approaches in accordance with Good Laboratory Practices (GLP).
• Develops methods and procedures for experiments and investigations.
• Writes and assists with experimental results for publication in technical and peer-reviewed journals.
• Analyzes and prepares reagent and/or assay product documentation.
• Organizes and procures needed reagents, performs experiments, analyzes data, and documents results.
• Documents current or new procedures or protocols for sample selection, data collection, data processing, and/or statistical estimation.
• Mentors, reviews, and supervises junior laboratory staff in the planning, execution, and analysis of experiments.
• Responsible for handling lab animals (mice) including general care, injections, sample processing, and euthanasia.
• May perform other duties and responsibilities as assigned or directed by the supervisor. This may include attendance of and participation in required training for role.

• Master’s Degree required, biological sciences preferred.
• Minimum of 3-5 years of experience required.

• Experience in orthotopic pancreatic and breast cancer model required.
• Experience with patient derived PDX and organoid model, subcutaneous, Intravenous (IV), Intraperitoneal (IP) injection, and including tail vein injection is preferred.
• Experience with small molecule and biologics in the context of cancer treatment is highly preferred.
• Knowledge of complex laboratory procedures such as multi- color flow cytometry, immunohistochemistry, recombinant protein purification, metabolomics experimentation.
• Animal handling experience required.
• Ability to meet deadlines of projects.
• Ability to follow complex instructions.
• Good communication, experiment documentation, protocol write up, and analytical skills required.
• Ability to obtain and maintain a T1/Public Trust background check

• Lifting:
  Requires lifting materials up to 10 lbs.
• Ability to stand or sit at a computer for prolonged periods

• This position will take place primarily in a laboratory setting.

• The annual salary range for this position is $61,000-$75,000. Actual salary will be determined based on experience, education, etc.

• HJF offers a comprehensive suite of benefits focused on your health and well-being, from medical, dental, and vision coverage to health savings and retirement plans, and more.

Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, education and credentials, a criminal background check, and a department of motor vehicle (DMV) check if applicable. Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer.

Equal Opportunity Employer/Protected Veterans/Individuals With Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.

41 CFR 60-1.35(c)