Senior Process Chemist

Who we are

DUDE CHEM is a Green Chemistry startup with its origins in the German Cluster of Excellence in Catalysis at the University of Technology Berlin. We are a small but mighty team which is dedicated to fulfil our mission:
Based on the 12 Principles of Green Chemistry we aim to build a green chemical-pharmaceutical industry. The industry currently consumes >13% of all fossil resources, most of them during the manufacturing. Our aim is to change this. In order to achieve this goal, we have built a strong IP portfolio and validated the tech onto the market in order to reduce or reuse expensive resources in the production of chemicals and pharmaceuticals.

We believe that digitalization can be an integral tool for the implementation of greener, more sustainable production processes. This is why we combine both scientific disciplines – digitalization and sustainability – in all of our projects. Over the last years, our team has proven that our approaches work and created hard competitive advantages in the core of the value chain of their customers.

Why we need you

We have recently secured a financing round in order to bring our first, greener manufactured products into the plants. Further, many customers are approaching us in order to get our support and help them to produce in a more sustainable and controlled way. Thus, we need your help to bring our greener processes into manufacturing as part of our Chemistry & Engineering Team.

In this role you will support our development team with your know-how in process chemistry, in the assessment of greener synthesis routes, the development of our green chemical processes, and scale-ups to the manufacturing plant. You will support us in establishing and shaping our process chemistry capabilities and strategy as the company grows into the future. If you want to develop innovative green chemical manufacturing processes, bring them from the lab scale into the plant scale and have a real positive impact on the world, you are the perfect match for us!

Results we expect

As a Senior Process Chemist we expect you to help develop our processes across the process development life cycle, from route design to process validation and manufacturing. You will be working in a multidisciplinary team developing our green processes, using your organic and process chemistry knowledge and creative problem-solving skills.

• Scalable and greener routes designed in collaboration with our synthesis chemists.
• Planned, executed and analysed small scale laboratory experiments in collaboration with our lab technicians to develop our green processes.
• Identification and removal of impurities from our reaction process steps in collaboration with our analytical chemists.
• Processes that are scalable, developed in collaboration with our process engineers.
• Tested synthesized material in collaboration with our synthesis chemists and lab technicians.
• Successful tech-transfer to our manufacturing partners.
• Control strategies for the processes and materials in our developed processes, in collaboration with our analytical chemists

Skills and attitudes that might be helpful

• Degree (M.Sc., Dipl.
  
  -Ing or PhD, or equivalents) in chemistry, natural sciences, or a related discipline.
• 3 years of experience working in the pharmaceutical or fine chemical industry in Chemical Process Development & Manufacturing.
• Experience developing and scaling synthesis processes, including common unit operations such as reactions, work-ups and crystallizations.
• Demonstrated expertise in reaction optimisation, including the application of Design of Experiments (DoE) and kinetic modelling/optimisation techniques.
• Experience supporting late-phase development of Active Pharmaceutical Ingredients (APIs), including identification and control of Critical Process Parameters (CPPs), Critical Material Attributes (CMAs), and establishment of design space.
  
  Hands-on experience developing robust processes suitable for large-scale manufacturing, with a track record of effective collaboration with
• Contract Development and Manufacturing Organizations (CDMOs).
• Experience with regulatory authoring and submissions and authoring of…