Principal Engineer; dfm

Why us

We believe that AI has the potential to revolutionize how cancer and other complex diseases are diagnosed and treated. We also believe that AI is a tool not an identity without access to high-quality data and a scientifically rigorous transparent approach to model development AI is just a buzzword. That’s where we come in.

Aignostics is a spin‑off from one of Europe’s largest and most prestigious university hospitals (Charité) with employees in Berlin and New York. We have received over $50M in funding from leading investors and are a growing team of over 100 interdisciplinary professionals. We work with academic partners as well as leading global life sciences companies.

As a Principal Engineer at Aignostics you will play a crucial role in shaping the technical direction and architectural integrity of our technical platform and products. You will work hand in hand with our collaborators in academia and industry to push the state of the art for digital pathology. Your expertise will be instrumental in driving technical excellence across all engineering teams ensuring we deliver high‑quality scalable solutions that transform complex biomedical data into actionable insights for cancer research and diagnostics.

You will report directly to our Sr. Vice President of Product & Engineering.

This is a unique opportunity to join a fun diverse and growing team of 100 software engineers, applied scientists, biologists and pathologists to shape the next generation of cancer treatments. You will be part of a driven community that works in an agile supportive and interdisciplinary research environment where your results make a difference to our established startup. You have the opportunity to grow personally and technically, take on significant responsibilities and benefit from a dynamic work environment.

At Aignostics we believe that fighting cancer is a job for people of all identities, backgrounds and cultures. We value and celebrate diversity and inclusion and are committed to offering equal employment and promotion opportunities for all applicants and employees.

• Own the technical direction and architectural integrity of our platform
• Advise our CTO and Sr. Vice President of Engineering on the technical vision of Aignostics
• Align our technical strategy with business objectives to provide a competitive advantage
• Resolve technical conflicts across teams and harmonize technologies to unlock synergies
• Advise product management on technical feasibility, cost and risks of complex product features
• Drive technical design planning and integration of our platform across systems
• Provide technical guidance in system design reviews for all teams
• Educate senior and mid-level engineers to bring them up to the next level
• Demonstrate long‑term thinking and utmost technical excellence in your individual contributions
• Lead the technical strategic planning and execution across the Tech Orgs quarterly roadmap
• Champion the drive for the highest standards across engineering teams
• Drive yearly operational readiness reviews of our systems collaborating with owning teams
• Guide engineering teams in maintaining up-to-date high-quality documentation and code

• Advanced degree in Computer Science, Software Engineering or a related field
• 10 years of software development experience with at least 5 years in senior technical leadership roles
• Proven track record of driving technical excellence and innovation in organizations with 50 engineers
• Excellent communication skills able to articulate complex technical concepts to both technical and non‑technical stakeholders
• Solid background in large scale systems and software architecture design patterns and clean coding
• Extensive experience in designing and implementing large-scale distributed and event-driven systems
• Extensive experience with data processing at scale
• Extensive expertise in multiple programming languages and frameworks
• Deep understanding of cloud technologies (GCP AWS), containerization and orchestration (Kubernetes)
• Familiarity with Dev Sec Ops  and MLOps practices, complex CI / CD pipelines and infrastructure as code

• Have…