Sr. Associate Scientist​/Scientist - Cell Biology & Immunology

Sr. Associate Scientist/Scientist - Cell Biology & Immunology Base pay range

$98,000.00/yr - $/yr

Senior Associate Scientist/Scientist – Cell Biology & Immunology

Company Overview:

Prellis Biologics is a dynamic startup revolutionizing the field of immunology. We are developing next-generation technologies to harness the full potential of the immune system, driving innovation in therapeutic development.

Position Overview:

We are seeking a passionate and skilled immunologist to help advance our pioneering in vitro immune system platform. In this role, you will collaborate with a multidisciplinary team to engineer lymph node organoids, design and execute high-impact assays, and contribute to the development of immune processes and antibody engineering strategies.

Key Responsibilities:

• Design, execute, and analyze complex cell-based experiments aligned with research objectives.
• Isolate, culture, and maintain both primary and established immune cell lines using aseptic techniques.
• Perform multiparameter flow cytometry and cell sorting for immune profiling and functional assays.
• Utilize innovative approaches to stimulate and characterize immune cell responses.
• Contribute scientific insight to the design and development of in vitro immune processes and antibody generation strategies.
• Maintain a hands‑on presence in the lab (60–80% of the time) in a fast‑paced research environment.
• Develop, optimize, and run immune assays, including ELISA and other protein quantification methods.
• Perform basic protein assays such as Western blotting and protein quantification.
• Ensure all experimental work complies with established protocols, SOPs, and regulatory standards.
• Maintain accurate, detailed, and traceable experimental records.
• Analyze, interpret, and present findings at internal meetings and project reviews.
• Support troubleshooting, protocol refinement, and continuous improvement initiatives.
• Collaborate with cross‑functional teams to align project goals and share expertise.

Qualifications:

• M.S. or Ph.D. in Immunology, Cell Biology, Biotechnology, or a related discipline.
• 5+ years of laboratory experience in immunology or cell biology (industry experience preferred).
• Strong understanding of adaptive immunity, particularly B and T cell biology.
• Knowledge of cell‑cell interactions and ligand‑receptor signaling pathways.
• Proficiency in mammalian cell culture, immune cell isolation, and maintenance.
• Demonstrated expertise in flow cytometry, including panel design, staining, acquisition, and analysis.
• Experience in immune functional assays, ELISA, and protein analysis techniques.
• Familiarity with laboratory compliance standards, SOPs, and documentation best practices.
• Strong organizational skills, attention to detail, and ability to work independently or collaboratively.
• Effective verbal and written communication skills for data reporting and documentation.
• Expertise in experimental design, data interpretation, and complex immunological data analysis.
• Proficiency in primary cell isolation, culture, and in vitro assay development.

Preferred

Skills & Experience:

• Knowledge of immune tolerance, vaccine development, or systems immunology.
• Experience in project management.
• Background in protein or sequence bioinformatics.
• Familiarity with molecular biology techniques.
• Experience implementing lab systems or high-throughput screening platforms.
• Skilled in data analysis tools such as Flow Jo, and Graph Pad Prism.
• Prior experience in drug discovery, vaccine and/or antibody development.

Key Attributes:

• Detail-oriented with a strong sense of responsibility for compliance and documentation.
• Proactive, collaborative, and adaptable in a dynamic research setting.
• Committed to scientific rigor and continuous professional development.

About Prellis Biologics

At Prellis we integrate human biology with machine learning. We aim to revolutionized drug discovery by harnessing the power of human immune system with tightly, integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human body candidate rapidly…