Vice President, Distribution & Trade – Market Access Field

Overview

Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study.

Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico;
Biogen receives exclusive rest of world commercialization rights.

STK-002 is Stoke’s proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals.

Stoke’s initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company’s proprietary approach.

The Vice President, Distribution & Trade – Market Access Field will be responsible for designing, implementing, and managing Stoke’s specialty distribution strategy for its first potential commercial product. This role will ensure seamless patient access, compliant operations, and a best-in-class distribution model tailored for zorevunersen.

Reporting to the VP of Market Access, this individual will serve as the company’s lead expert on trade and channel distribution, overseeing partnerships with specialty distributors (SDs), specialty pharmacies (SPs), and third-party logistics (3PL) providers.

The ideal candidate brings deep operational experience in specialty product distribution, rare disease commercialization, state licensing, and DSCSA serialization.

• Distribution & Trade Strategy
  Design and execute the U.S. specialty distribution and trade strategy aligned with the product access and commercial plan.
• Distribution & Trade Strategy
  Establish and manage relationships with channel partners (SDs, SPs, 3PLs) to ensure timely, compliant product distribution.
• Distribution & Trade Strategy
  Lead selection, contracting, and performance management of all trade and distribution vendors.
• Distribution & Trade Strategy
  Develop and monitor SLAs, KPIs, and reporting to ensure optimal service levels and inventory management.

• Oversee the operational readiness of the distribution network to support launch, including order management, returns processing, and product traceability.
• Manage day-to-day trade operations, including data flow, order-to-cash processes, and performance reviews with distribution partners.
• Ensure DSCSA serialization and traceability compliance across the distribution network.
• Oversee state licensing activities related to product distribution and ensure all licenses are obtained, maintained, and compliant with federal and state regulations.

• Partner closely within Market Access and across Finance. Supply Chain, Quality, Regulatory, and Patient Services to ensure an integrated, compliant, and patient-centered distribution model.
• Collaborate with Supply Chain and Quality to align on product release, distribution, and logistics.
• Support Finance and Legal in contract negotiation, distribution fee structures, and compliance with fair market value standards.

• Ensure all trade and distribution activities comply with DSCSA, PDMA, GDP, and other applicable regulations.
• Develop and maintain standard operating procedures (SOPs)…