Cardiologist Translational Medicine Expert; TME

Job Title

Cardiologist Scientist Associate Director Level 5 / Cardiologist Scientist Director Level 6 (responsibilities commensurate with the successful candidate’s level of expertise).

Location:

Basel, Switzerland.

Level 5

Bio Medical Research (BR) is the innovation engine of Novartis, collaborating across the company and beyond to develop technologies with the potential to produce therapeutic breakthroughs. Translational Medicine (TM) is the clinical research arm of  , comprising around 900 associates globally. TM plays a pivotal role in moving medicines from research advances to patients by bridging drug discovery and clinical application.

The TM Discovery & Profiling (TMDP) group of physicians and clinical researchers drives science from discovery to patient through selection, profiling, and effective development of medicines. Translational medicine experts oversee Phase 1 and 2 trials to demonstrate proof‑of‑concept (PoC) and support Phase 3 development. They are key members of global cross‑functional project teams that design and implement early research projects culminating in clinical PoC studies.

By collaborating with biology and chemistry colleagues, they identify disease targets with unmet medical needs and contribute to clinical development pathways. The PoC studies they lead are critical steps in drug development er PoC, if the program progresses to full development, the translational medicine expert continues as a key member of the full development team through registration.

#LI-Hybrid

As a Cardiovascular Metabolism (CVM) TM Expert you will collaborate with the CVM TM Head or other experienced TM experts to develop high‑value decision strategies for the translational component of drug development projects and lead global cross‑functional teams through the PoC phase and beyond.

• Lead global project teams through the PoC phase to drive implementation of the PoC strategy; participate in project teams throughout the program life cycle from NTRC to registration.
• Responsible for the clinical portions of the Integrated Development Plan (IDP) through PoC.
• Act as medical monitor for one or more clinical studies.
• Communicate clinical team matters to project teams and relevant Decision Boards (e.g., Disease Area Decision Board).
• Convene internal and external leaders to consider the proposed approach to PoC.
• Evaluate clinical centers and foster communication with collaborating investigators.
• Oversee publication and external presentation of PoC clinical study results.
• Accountable for compound‑related biomarker strategies; work closely with biomarker experts in implementation.
• In collaboration with research scientists, identify, develop, and implement strategy for preclinical support of program‐related objectives, including assessment of medical‑need proposals for clinical development pathways and review of preclinical data for clinical implications.
• Participate in team presentations to Health Authorities as the TM Expert.

• Doctoral degree (MD required) with clinical subspecialty training preferred in cardiovascular disease or endocrinology/metabolic disease; additional PhD/post‑doctoral research experience preferred.
• At least 1–2 years of experience in a pharmaceutical/biotech company, CRO, or academic medical center or related experience; 5+ years to be considered for the Director level.
• Recognized for medical expertise.
• Recognized for scientific expertise: respected by colleagues internally and externally, having made significant contributions to the field, created or established new concepts, and possessing a record of high‑quality publications in international scientific journals.
• Excellent written, oral, and presentation communication skills.
• Independence:
  Able to work independently on study planning and execution and with supervision on project planning.
• Leadership of collaborations:
  Able to lead multidisciplinary teams in a matrix organization.
• Innovation:
  Seeks out new clinical discovery opportunities and PoC approaches.
• Additional consideration for candidates with advanced research experience in data science, genetics/genomics, AI, or digital methods in electrocardiography and/or cardiovascular imaging.
• Demonstrated passion for science.

Novartis is committed to building an outstanding inclusive work environment and diverse teams representative of the patients and communities we serve.

Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process or to obtain more detailed information about the essential functions of a position, please send an e‑mail including the job requisition number and the nature of your request and your contact information.