Associate Medical Director

GRANITE BIO is seeking a Associate Medical Director

GRANITE BIO is a private biotechnology company located in Basel (Switzerland).

GRANITE BIO is supported by top‑tier investors with ~$100M raised to date. Based on fundamental research conducted over the last two decades, GRANITE BIO’s is pursuing a differentiated approach to transform inflammatory, autoimmune, and fibrotic conditions. Both our programs are first‑in‑class monoclonal antibodies for large market opportunities in Immunology and Inflammation. GRT‑001, the lead asset, depletes inflammatory monocytes. It has just completed a Phase 1a trial in healthy volunteers and has shown favourable safety and pharmacodynamic effect.

The Phase 1b trial in patients with Ulcerative Colitis has just started. GRT‑002 is an IL‑3 neutralising antibody that is thought to play an important role in type II inflammation.

Our company fosters an open, inter‑disciplinary, diverse, international and creative working environment. We enable work‑from‑home options according to our internal workflows. The successful candidate will be highly motivated and enthusiastic with a positive “can do” attitude, attention to details and innovation, strong organisational and communication skills.

• Design, execution/conduct and report of Ph1/2 clinical trials in I&I space
• Contribute to medical leadership team and clinical development strategy
• Provide guidance and expertise in the development of clinical trial protocols and further study relevant documents, such as ICF, IB, SoA, TPP, SAP etc
• Ensure that safety and efficacy data is generated and analysed according to GCP/SOPs, corporate strategy and timelines.
• Perform medical monitoring activities (such as medical oversight of the study, answer questions about eligibility, review safety and adverse event data, medical oversight of coding activities)
• Work closely with cross‑functional team members to ensure planning and execution of clinical trials to meet key study milestones
• Play a key role in the development of statistical analysis plan, and in the review, interpretation, and communication of clinical trial data from clinical trials.
• Author and develop clinical documents like, clinical study protocols and amendments and review other clinical documents like safety management plan, medical monitoring plan
• Work closely with colleagues from Clinical Operations and Clinical Biomarker department to deliver clinical study programme goals and milestones

• You have an advanced medical degree (MD) or equivalent
• You have at least 3 years of clinical research or clinical development experience in pharmaceutical/biotechnological industry, ideally in early clinical trials
• You can develop collaborative working relationships with physicians, expert consultants and contracted vendors
• You have a strong analytical mindset, excellent written/verbal communication skills
• You have exceptional attention to detail, organisational skills and judgement
• You have strong knowledge of clinical trial methodology, regulatory and compliance requirements of clinical trials
• You have knowledge of Good Clinical Practices / Good laboratory Practices and clinical study design
• You are a talented, pro‑active and passionate medical professional, inspired by our shared vision to bring innovation to patients with unmet medical needs.
• You are eager to work within a dynamic and fit‑for‑purpose Biotech environment.
• You understand the framework and complexities of early clinical multi‑centre trials and can deal with various CRO/CDO‑related ways of working.
• You have ideally experience in the autoimmune disease and/or IBD (I&I) space
• You are an effective communicator that shares information transparently and strategically.
• You are a team player and an active listener.
• You thrive in environments of ambiguity and collaboration where authority is distributed between all of the people involved and where advice‑seeking is foundational.
• You apply your organising and problem‑solving skills to plan and run efficient operational and enabling aspects of clinical programmes, studies, and/or enabling projects.
• You thrive leading or being an active member of large or small diverse…