Lab Associate Cellular m functional and soluble Biomarkers KFR

Lab Associate for Cellular m functional and soluble Biomarkers (6805 – KFR)

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Lab Associate for Cellular m functional and soluble Biomarkers

Our client is a pioneer in Drug Discovery and Development and one of the front runners in Personalised Healthcare. As the world’s largest R&D spender in the pharmaceutical and diagnostics domain, they work in a vast number of drug discovery & therapeutic areas and are highly recognised internationally.

We are currently looking for a Lab Associate for Cellular m functional and soluble Biomarkers for an 18-month contract based in Basel, Switzerland.

This is an on-site and full-time role.

This position is situated within the Bioanalytics and Biomarkers Chapter of the Pharmaceutical Sciences function. Their chapter is accountable for developing Bioanalytical and Biomarker methods and implementing them in clinical studies to help guide drug development. They closely collaborate with different disease therapeutic areas and other functions to convert hypotheses into innovative therapeutics.

With their deep expertise in immunology, technology, and applied cellular and protein biomarker measurement, our client shapes and enables the implementation of innovative clinical biomarker strategies. They ensure the delivery of high‑quality, decision‑enabling data by leading method development, validation, data analysis, and laboratory selection. Their team continuously evaluates and integrates cutting‑edge technologies, always striving to apply the most effective approaches to address key biological questions and advance patient‑focused science.

• Designing, developing, and transferring biomarker assays that support clinical trials.
• Lead in‑house assay development, support method transfers to external CRO partners, and ensure the generation of robust, high‑quality biomarker data from method development through to clinical sample analysis.
• Self‑driven planning, development, troubleshooting and critical analysis of results of analytical methods for complex cellular, functional, and soluble protein biomarkers supporting preclinical and clinical drug development, in full compliance with regulatory and GxP requirements.
• Design and execute experimental protocols, generate, analyse, troubleshoot, interpret data, and deliver high‑quality reports aligned with project timelines.
• Support method transfer and implementation with external partners, ensuring proper documentation and efficient troubleshooting.
• Seek, evaluate and introduce novel technologies to enhance biomarker strategies and expand their application across therapeutic areas.
• Collaborate with internal/external stakeholders to ensure data integrity, technical and scientific rigor, and timely resolution of technical challenges.
• Present activities and results on internal/external meetings.
• Contribute to a culture of innovation, continuous improvement, and compliance with Safety, Security, Health, and Environmental standards.

• Relevant working/residency permit or Swiss/EU‑Citizenship required
• Bachelor’s or Master’s degree (No PhD) in a relevant scientific discipline, with proven industry or CRO experience.
• Minimum of 2 years of experience in biomarker assay development within a regulated environment.
• Proficiency across diverse biomarker assay technologies, including:
  Cellular and functional assays—Flow cytometry, pFlow, ELISpot/Fluoro Spot, HTRF;
  Ligand‑binding assays—ELISA, ELLA, Simoa, Elecsys, MSD.
• Hands‑on experience in technology implementation, optimisation, and troubleshooting of bioanalytical/biomarker methods.
• Strong understanding of GxP principles.
• Experience supporting pharmacodynamic biomarker assay development for preclinical or clinical applications.
• Scientific credibility demonstrated through relevant publications and/or presentations at external conferences (1‑2 is enough).
• You are a proactive team‑player who values collaboration, continuous learning, and scientific excellence.

Associate

Temporary

Science