Senior Director, Alliance & Program Management

GRANITE BIO is a private biotechnology company located in Basel (Switzerland). GRANITE BIO is supported by top‑tier investors with ~$100M raised to date. Based on fundamental research conducted over the last two decades, GRANITE BIO’s differentiated approach transforms inflammatory, autoimmune, and fibrotic conditions through first‑in‑class monoclonal antibodies targeting large market opportunities in Immunology and Inflammation. GRT‑001, the lead asset, depletes inflammatory monocytes and has completed a Phase 1a trial in healthy volunteers with favorable safety and pharmacodynamic results;

the Phase 1b trial in patients with Ulcerative Colitis has just started. GRT‑002 is an IL‑3 neutralizing antibody that may play an important role in type II inflammation.

Our company fosters an open, interdisciplinary, diverse, international and creative working environment and offers flexible work‑from‑home options in accordance with our internal workflows. The successful candidate will be highly motivated, enthusiastic, with a positive “can do” attitude, attention to detail, innovation, strong organisational and communication skills.

Reporting directly to the CEO, the Senior Director, Alliance & Program Management will lead Alliance Management for our on‑going collaboration with a large pharmaceutical company, Program Management for both clinical‑stage assets, and Quality functions. The role partners closely with the executive team, clinical operations and finance to set operational priorities, optimise resource planning, and support execution of the company’s long‑term strategy.

• Serve as the primary operational and relationship lead for the company’s external development partner.
• Manage all collaboration governance, including Joint Steering Committee meetings and potential working groups.
• Ensure fulfillment of all contractual obligations, milestones, deliverables, reporting requirements and data‑sharing timelines.
• Coordinate cross‑functional inputs (clinical, CMC, regulatory, translational, finance, legal, IP) to prepare materials for governance meetings.
• Maintain strong, trust‑based relationships with partner counterparts and ensure clear, consistent communication.
• Track joint progress against agreed plans, identify emerging risks or misalignments, and facilitate timely issue escalation and resolution.

• Lead integrated development planning and track execution across company programs.
• Facilitate cross‑functional alignment and ensure issues or deviations are surfaced and resolved efficiently.
• Provide program updates and recommendation briefs to executive leadership and the Board.

• Provide leadership and general oversight of the QA function, communicating clear priorities and overseeing the implementation of quality activities that meet regulatory and company expectations.
• Review and monitor the QA function plans and progress, ensuring issues are addressed appropriately and escalated if needed, timelines are met, and the organization maintains effective quality processes and inspection readiness.
• Oversee GxP Quality Systems appropriate for clinical‑stage operations, ensuring compliance with regulatory expectations.

• Demonstrated alliance management experience in the biotech sector, ideally managing strategic development collaborations with large pharmaceutical partners.
• Strong clinical‑stage drug development programme management experience, including planning and execution of development programmes in early to mid clinical stages.
• Demonstrated capability to lead cross‑functional teams and manage complex, multi‑party collaborations.
• Proven ability to operate both strategically and hands‑on in a fast‑paced, resource‑constrained environment.
• Proven ability to manage governance structures such as Joint Steering Committees and cross‑company working groups.
• Excellent communication, negotiation and relationship‑building skills.
• Experience operating in clinical‑stage biotech environments with evolving processes and high strategic impact.

• Offices: Our well‑equipped laboratories and offices are located at the Tech Park, a premier address for…