Senior Expert Science & Technology; Analytical Chemistry Oligonucleotides

Job Description Summary

Location:

Basel, Switzerland #onsite

Role

Purpose:

We are seeking a highly motivated PhD level analytical chemist to strengthen and expand our capabilities in mixed modalities across the organization. In this role, you will apply your scientific expertise to shape analytical strategies for oligonucleotide development, with the possibility for the scope to expand to other new therapeutic modalities as the portfolio evolves, ensuring high quality delivery of new therapeutic candidates.

• With your strong expertise and creativity in analytical development, you are accountable for establishing future analytical control strategies and standards for oligonucleotide projects
• In our labs, your experimental designs will be executed and allow you to interpret and report data and results
• Further, you will coordinate and plan all cGMP related activities for starting materials and intermediates to ensure timely manufacture under GMP within Chemical & Analytical Development.
• As a core member of a cross functional team, you collaborate closely with our internal and external partners to ensure timely and quality delivery of new nucleotide drugs to our patients
• Further, you will provide relevant process documentation in support of filing of dossiers
• You will also actively participate in scientific exchange groups within Novartis and Academia, as well as maintain excellent collaborations with our customers.

• PhD in analytical chemistry / pharmaceutical analysis ideally with specialization in the field of oligonucleotide analytics.
• Minimum of 3 years of relevant experience in pharmaceutical analysis, ideally in the context of complex molecules or emerging modalities.
• Scientific curiosity coupled with recognized achievements in the development of new analytical methods using advanced separation technologies (e.g. UHPLC operated in various modes: RP, HILIC, IP, AEX, SEC, 2D), and related hyphenated detection technology including CAD and MS.
• Strong experience in developing analytical methods using high‑resolution mass spectrometry (HRMS), including advanced data processing, interpretation, and evaluation supported by relevant software tools.
• Dedicated, thoughtful and flexible team working skills.
• Good knowledge of English (oral and written) is required, good command of German (spoken/ written) is desirable.
• Excellent knowledge of laboratory and/or technical tools

• Several years relevant professional experience in field of analytical development
• Good knowledge of software and computer tools such as Office package and relevant analytical software suites (e.g. Chromeleon, Xcalibure, Open Lab 2, Genedata)

You’ll receive:
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Commitment to Diversity and Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.