Biorepository Technician

CNAG – The Institute

The Centro Nacional de Análisis Genómico (CNAG) is a world-leading genomics research institute located in Barcelona.

With state-of-the-art genomic analysis capabilities, CNAG supports national and international researchers, as well as clinicians, in their pursuit of cutting-edge research and clinical applications.

The CNAG carries out genomic analysis projects of any scale to improve quality of life in collaboration with the Spanish, European and international research community. CNAG is one of the largest genome analysis centers in Europe, with Illumina, Oxford Nanopore Technologies and Pacific Biosciences sequencers, state-of-the-art single-cell equipment, and an extensive computing infrastructure. The operation is certified according to ISO 9001 and ISO 27001 and accredited according to ISO 17025, delivering standardized, high-quality data for research and clinics.

The CNAG has more than 130 professionals who participate in major International Genome Initiatives and EU funded projects. The institute is structured into different teams, units and groups, spanning from Bioinformatics, Sequencing, Single-cell, to Corporate Management.

About the Unit/ Team

The Biorepository team is a part of the Sequencing unit that provides highly specialized support in next generation genomics to national and international researchers and clinicians and conducts strategic development and implementation of the protocols.
It assesses DNA/RNA extraction procedures used by collaborators, evaluates sample suitability for CNAG sequencing applications, and coordinates sample shipments. The biorepository also ensures appropriate sample storage under highly controlled conditions and distributes working aliquots to the Sample Preparation and Long Read Sequencing teams. The contract will be funded by the Carlos III Health Institute through project “PMPER
24/00002,” financed by the European Union – NextGenerationEU

The Role

The successful candidate will work closely with the Biorepository Manager and team members, and the Head of the Sequencing Unit to maintain, develop, implement, and run protocols within the Biorepository team.

Responsibilities:

Sample reception, verification, and LIMS data entry.
DNA and RNA samples quality control.
Preparation of aliquots for sequencing, manually and using automated systems.
Development and implementation of new quality control protocols and integration of new instruments
Sample data management through CNAG LIMS tools.
Keeping rigorous audit trails of the work carried out, writing and updating documentation such as Standard Operating Procedures (SOPs).
Recognizing and reporting erroneous protocol outcomes.
Stock and orders management.

Professional experience

At least 3 years of work experience in molecular biological laboratory, in particular using: DNA/RNA extraction procedures, DNA/RNA quality control, quantification techniques, gel electrophoresis, PCR and other enzymatic reactions.
At least 1 year of work experience in data base use, especially lab centered (LIMS).

Experience with liquid handling robots.

Experience with capillary electrophoresis instruments
Experience in ISO certified/accredited environments.

Must Have

Excellent laboratory techniques and able to work very reliably, pay attention to detail and work as part of a team
Proactive and autonomous attitude
Capability to work with computers and common software packages
Automation and instrumentation competence
The emphasis will be on excellent laboratory practices
Fluent in English
Advanced MS Office skills

Nice to have

Experience with biobanking or biorepository workflows for sequencing applications
Knowledge of sample traceability, chain of custody, and documentation.
Experience coordinating sample shipments and logistics.
Familiarity with regulatory or ethical requirements related to biological samples.

Competences

Responsible and reliable working attitude, with willingness to learn.
Good organizational and time-management skills in a supervised laboratory environment.
Ability to follow SOPs, instructions, and established workflows.
Attention to detail and commitment to good laboratory practices.
Ability to recognize routine issues and…